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Cleaning Validation Support

A validation for cleaning involves testing for acceptable residues on GMP manufacturing surfaces, including medical device and pharmaceutical.  See below for appropriate analytical methods, see white papers and the Aqueous Cleaning Handbook additional information.

Residue identification and detection involves testing using analytical methods which can be provided by Alconox Inc. technical support. The following methods can be used to detect Alconox Inc. detergents:

Alcojet® Low Foaming Powdered Detergent
  • Organic Carbon by TOC
  • Conductivity
  • Phosphate by Titration or IC
  • EDTA by HPLC
Alconox® Powdered Precision Cleaner
  • Anionic Surfactant by HPLC
  • EDTA by HPLC
  • Direct UV/Vis
  • Organic Carbon by TOC
  • Conductivity
  • Phosphate by Titration and IC
Alcotabs® Tablet Pipet Detergent
  • Anionic Surfactant by HPLC
  • EDTA by HPLC
  • Direct UV/Vis
  • Phosphate by Titration and IC
  • Organic Carbon by TOC
  • Conductivity
  • Organic Acid by HPLC, UV or Assay
Citrajet® Low-foam Liquid Acid Cleaner/Rinse
  • Organic Carbon by TOC
  • Organic Acid by HPLC, UV, or Assay
Citranox® Liquid Acid Cleaner and Detergent
  • Anionic Surfactant by HPLC
  • Direct UV/Vis
  • Organic Carbon by TOC
  • Conductivity
  • Organic Acid by HPLC, UV, or Assay
Detojet® Low-Foaming Liquid Detergent
  • Conductivity
  • Phosphate by Titration and IC
  • Organic Carbon by TOC
  • Organic Acid by HPLC, UV or Assay
  • Potassium by flame or IC
Detonox® Ultimate Precision Cleaner
  • Anionic Surfactant by HPLC
  • EDTA by HPLC
  • Direct UV/Vis
  • Phosphate by Titration and IC
  • Organic Carbon by TOC
  • Conductivity
  • Potassium by flame or IC
Keylajet® Low-Foaming High-Alkaline Liquid
  • EDTA by HPLC
  • Phosphate by Titration and IC
  • Organic Carbon by TOC
  • Conductivity
  • Organic Acid by HPLC, UV or Assay
  • Potassium by flame or IC
Liquinox® Critical Cleaning Liquid Detergent
  • Anionic Surfactant HPLC
  • Direct UV/vis
  • Organic Acid by HPLC,  UV or Assay
  • Organic Carbon by TOC
  • Conductivity
Luminox® Low-Foaming Neutral pH Liquid Detergent
  • Organic Carbon by TOC
  • Organic Acid by HPLC, UV or Assay
Solujet® Low-Foaming Phosphate-Free Liquid
  • Organic Carbon by TOC
  • Conductivity
  • Organic Acid by HPLC, UV or Assay
  • Potassium by flame or IC
Tergajet® Low-Foaming Phosphate-Free Powder
  • Organic Carbon by TOC
  • Conductivity
  • Organic Acid by HPLC, UV or Assay
  • EDTA by HPLC
Tergazyme® Enzyme-Active Powdered Detergent
  • Anionic Surfactant by HPLC
  • EDTA by HPLC
  • Direct UV/Vis
  • Organic Carbon by TOC
  • Conductivity
  • Phosphate by Titration and IC
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